Cancer Currents: An NCI Cancer Research Blog
A blog featuring news and research updates from the National Cancer Institute. Learn more about Cancer Currents.
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Blocking Calcium Transfer May Selectively Kill Cancer CellsA new study shows that blocking the transfer of calcium ions (Ca2+) into mitochondria is toxic to cancer cells and impairs growth of tumors in mice, while sparing normal cells.
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New Strategy for Treating Advanced Ovarian Cancer Shows Promise in MiceThe use of a protein fragment to stimulate cells in the tumor microenvironment against cancer shows promise in animal models of metastatic ovarian cancer.
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Crizotinib Approval Expanded for Advanced Lung CancerThe FDA has approved uses of the targeted therapy crizotinib (Xalkori®) for patients with advanced lung cancer whose tumors have alterations in the ROS1 gene.
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What’s New on NCI’s Websites?NCI periodically provides updates on new websites and other online content of interest to the cancer community.
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High-Magnification Microscopy Visualizes Tumor Blood Vessels in Real TimeHigh-powered intravital microscopy reveals that 50 percent of blood vessels in melanoma tumors do not have any blood flow, according to a new study.
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Keeping Pace: How New Data Can Affect Ongoing Clinical TrialsResearch results sometimes outrace the design of an ongoing clinical trial and the trial has to be recalibrated to include newer treatments, according to NCI’s Dr. Jo Anne Zujewski.
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Novel Strategy Isolates Immune Cells in the Blood that Recognize MelanomaNCI scientists have developed a novel strategy for identifying immune cells circulating in the blood that recognize specific proteins on tumor cells, a finding they believe may have potential implications for immune-based therapies.
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HPV Infections Targeted by Vaccine Decrease in U.S.Infection with human papillomavirus (HPV) types targeted by the quadrivalent HPV vaccine has declined by nearly two-thirds among teenage girls since HPV vaccination was recommended in the United States.
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Fueling Basic Discovery: NCI’s Cooperative Human Tissue NetworkQuality biospecimens are a foundational resource for cancer research. One of NCI’s longest running biospecimen programs is the Cooperative Human Tissue Network, a resource mainly for basic discovery and early translational research.
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BRCA Testing Rates High in Young Women with Breast Cancer
Testing for genetic mutations strongly associated with an increased risk of breast cancer has risen dramatically among women younger than age 40 who are diagnosed with the disease, according to a new study.
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Missed Radiation Therapy Sessions Increase Risk of Cancer RecurrencePatients who miss radiation therapy sessions during cancer treatment have an increased risk of their disease returning, even if they eventually complete their course of radiation treatment, according to a new study.
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Study of Cancer’s Origins Reveals Genetic Reprogramming of Single CellsResearchers have used a new zebrafish model of cancer to characterize the early genetic changes associated with the initiation of tumors.
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Gene Fusion May Drive Rare Childhood Brain TumorResearchers have identified a genetic rearrangement that may drive the development of a rare benign brain tumor in children through three distinct biological mechanisms simultaneously.
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What’s New on NCI’s Websites?NCI is constantly publishing new information on its websites, so periodically we provide updates on new content of interest to the cancer community.
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NCI-DOE Collaboration Paving Way for Large-Scale Computational Cancer ScienceNCI and the Department of Energy have entered into a collaboration to develop a plan to use large-scale computing to influence cancer science and, ultimately, clinical treatment.
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Prospective Study Links HPV Detection in the Mouth to Head and Neck CancerA new study confirms that infection with HPV 16 precedes the development of head and neck cancer.
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FDA Approves Eribulin Mesylate for Advanced LiposarcomaThe FDA has approved eribulin mesylate for patients with liposarcoma whose cancers are advanced or cannot be removed by surgery and are no longer responding to anthracycline-based chemotherapy.
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President Obama’s Budget Request Affirms Commitment to Progress against CancerPresident Obama’s FY 2017 Budget Request includes $680 million to support Vice President Biden’s cancer research initiative.
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Mouse Study Points to Mechanism Linking Obesity and Colorectal Cancer RiskA missing hormone in obese mice may help explain a longstanding association between obesity and an increased risk of colorectal cancer in humans.
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Persistent Peripheral Neuropathy Increases Fall Risk among Cancer SurvivorsMany female cancer survivors have problems with mobility and other physical functioning as a result of persistent peripheral neuropathy caused by chemotherapy treatment, according to a new study.